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1

Safety of Ocrelizumab in Multiple Sclerosis: Updated Analysis in Patients with Relapsing and Primary Progressive Multiple Sclerosis

Alroughani, Raed, Hauser, Stephen L., Kappos, Ludwig, Montalban, Xavier, Craveiro, LicÃnio, Hughes, Richard, Mcnamara, John, Pradhan, Ashish, Wormser, David, Koendgen, Harold

Journal:

Multiple Sclerosis and Related Disorders

Année:

2020

Langue:

english

Fichier:

PDF, 99 KB

english, 2020

2

Siponimod for patients with relapsing-remitting multiple sclerosis (BOLD): an adaptive, dose-ranging, randomised, phase 2 study

Selmaj, Krzysztof, Li, David KB, Hartung, Hans-Peter, Hemmer, Bernhard, Kappos, Ludwig, Freedman, Mark S, Stüve, Olaf, Rieckmann, Peter, Montalban, Xavier, Ziemssen, Tjalf, Auberson, Lixin Zhang, Pohl

Journal:

The Lancet Neurology

Année:

2013

Langue:

english

Fichier:

PDF, 445 KB

english, 2013

3

Natalizumab treatment for multiple sclerosis: updated recommendations for patient selection and monitoring

Ludwig Kappos, David Bates, Gilles Edan, Mefkûre Eraksoy, Antonio Garcia-Merino, Nikolaos Grigoriadis, Hans-Peter Hartung, Eva Havrdová, Jan Hillert, Reinhard Hohlfeld, Marcelo Kremenchutzky, Olivier

Journal:

The Lancet Neurology

Année:

2011

Langue:

english

Fichier:

PDF, 414 KB

english, 2011

4

Serum neurofilament light: A biomarker of neuronal damage in multiple sclerosis

Disanto, Giulio, Barro, Christian, Benkert, Pascal, Naegelin, Yvonne, Schädelin, Sabine, Giardiello, Antonella, Zecca, Chiara, Blennow, Kaj, Zetterberg, Henrik, Leppert, David, Kappos, Ludwig, Gobbi,

Journal:

Annals of Neurology

Année:

2017

Langue:

english

Fichier:

PDF, 1.25 MB

english, 2017

5

[Lecture Notes in Mathematics] Symposium on Probability Methods in Analysis Volume 31 || Representation of abstract L-spaces

Grenander, Ulf, Guber, Siegfried, Jacobs, Konrad, Kappos, Demetrios A., Kellerer, Hans G., Kendall, David. G., Kounias, Eustratios, Kristensen, Povl, Mejlbo, Lars, Poulsen, Ebbe Thue, Loynes, R. M., L

Année:

1967

Langue:

english

Fichier:

PDF, 638 KB

english, 1967

6

[Lecture Notes in Mathematics] Symposium on Probability Methods in Analysis Volume 31 || Comments on the Martingale Convergence Theorem

Grenander, Ulf, Guber, Siegfried, Jacobs, Konrad, Kappos, Demetrios A., Kellerer, Hans G., Kendall, David. G., Kounias, Eustratios, Kristensen, Povl, Mejlbo, Lars, Poulsen, Ebbe Thue, Loynes, R. M., L

Année:

1967

Langue:

english

Fichier:

PDF, 345 KB

english, 1967

7

Dynamic susceptibility contrast MR imaging of plaque development in multiple sclerosis: Application of an extended blood-brain barrier leakage correction

Reta Haselhorst, Ludwig Kappos, Deniz Bilecen, Klaus Scheffler, David Möri, Ernst W. Radü, Joachim Seelig

Journal:

Journal of Magnetic Resonance Imaging

Année:

2000

Langue:

english

Fichier:

PDF, 367 KB

english, 2000

8

Health-related quality of life in multiple sclerosis: effects of natalizumab

Richard A. Rudick, Deborah Miller, Steve Hass, Michael Hutchinson, Peter A. Calabresi, Christian Confavreux, Steven L. Galetta, Gavin Giovannoni, Eva Havrdova, Ludwig Kappos, Fred D. Lublin, David H.

Journal:

Annals of Neurology

Année:

2007

Langue:

english

Fichier:

PDF, 306 KB

english, 2007

9

Correction: Prognostic implications of a carefully performed neurological assessment in patients with a first event suggestive of multiple sclerosis

Jessica M Nielsen, Christoph Pohl, Chris H Polman, Frederik Barkhof, Mark S Freedman, Gilles Edan, David H Miller, Lars Bauer, Rupert Sandbrink, Ludwig Kappos, Bernard MJ Uitdehaag

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 146 KB

english, 2011

10

Antimyelin antibodies in clinically isolated syndromes correlate with inflammation in MRI and CSF

Jens Kuhle, Raija L.P. Lindberg, Axel Regeniter, Matthias Mehling, Francine Hoffmann, Markus Reindl, Thomas Berger, Ernst W. Radue, David Leppert, Ludwig Kappos

Journal:

Journal of Neurology

Année:

2007

Langue:

english

Fichier:

PDF, 270 KB

english, 2007

11

The efficacy of natalizumab in patients with relapsing multiple sclerosis: subgroup analyses of AFFIRM and SENTINEL

Michael Hutchinson, Ludwig Kappos, Peter A. Calabresi, Christian Confavreux, Gavin Giovannoni, Steven L. Galetta, Eva Havrdova, Fred D. Lublin, David H. Miller, Paul W. O’Connor, J. Theodore Phillips,

Journal:

Journal of Neurology

Année:

2009

Langue:

english

Fichier:

PDF, 170 KB

english, 2009

12

Facial nerve palsy and anti-Ku autoantibodies

Raoul Sutter, Bernard Mengiardi, Daniela Benz, Ingmar Heijnen, Ludwig Kappos, David T. Winkler

Journal:

Journal of Neurology

Année:

2012

Langue:

english

Fichier:

PDF, 204 KB

english, 2012

13

Strategies for optimizing MRI techniques aimed at monitoring disease activity in multiple sclerosis treatment trials

F. Barkhof, Massimo Filippi, David H. Miller, Paul Tofts, Ludwig Kappos, Alan J. Thompson

Journal:

Journal of Neurology

Année:

1997

Langue:

english

Fichier:

PDF, 62 KB

english, 1997

14

Sa.32. The Immunogenicity of Natalizumab in Patients with Multiple Sclerosis

Gavin Giovannoni, Paul O'Connor, Eva Havrdova, Michael Hutchinson, Ludwig Kappos, David Miller, J. Theodore Phillips, Chris Polman, Fred Lublin, Andrzej Wajgt, Frances Lynn, Michael Panzara, Alfred Sa

Journal:

Clinical Immunology

Année:

2006

Langue:

english

Fichier:

PDF, 43 KB

english, 2006

15

Multiple sclerosis as a generalized CNS disease—comparative microarray analysis of normal appearing white matter and lesions in secondary progressive MS

Raija L.P Lindberg, Corline J.A De Groot, Ulrich Certa, Rivka Ravid, Francine Hoffmann, Ludwig Kappos, David Leppert

Journal:

Journal of Neuroimmunology

Année:

2004

Langue:

english

Fichier:

PDF, 6.96 MB

english, 2004

16

A highly sensitive electrochemiluminescence immunoassay for the neurofilament heavy chain protein

Jens Kuhle, Axel Regeniter, David Leppert, Matthias Mehling, Ludwig Kappos, Raija L.P. Lindberg, Axel Petzold

Journal:

Journal of Neuroimmunology

Année:

2010

Langue:

english

Fichier:

PDF, 300 KB

english, 2010

17

Natalizumab treatment for multiple sclerosis: recommendations for patient selection and monitoring

Ludwig Kappos, David Bates, Hans-Peter Hartung, Eva Havrdova, David Miller, Chris H Polman, Mads Ravnborg, Stephen L Hauser, Richard A Rudick, Howard L Weiner, Paul W O'Connor, John King, Ernst Wilhel

Journal:

The Lancet Neurology

Année:

2007

Langue:

english

Fichier:

PDF, 249 KB

english, 2007

18

Long-term effect of early treatment with interferon beta-1b after a first clinical event suggestive of multiple sclerosis: 5-year active treatment extension of the phase 3 BENEFIT trial

Ludwig Kappos, Mark S Freedman, Chris H Polman, Gilles Edan, Hans-Peter Hartung, David H Miller, Xavier Montalbán, Frederik Barkhof, Ernst-Wilhelm Radü, Carola Metzig, Lars Bauer, Vivian Lanius, Ruper

Journal:

The Lancet Neurology

Année:

2009

Langue:

english

Fichier:

PDF, 239 KB

english, 2009

19

MRI characteristics are predictive for CDMS in monofocal, but not in multifocal patients with a clinically isolated syndrome

Jessica M Nielsen, Christoph Pohl, Chris H Polman, Frederik Barkhof, Mark S Freedman, Gilles Edan, David H Miller, Lars Bauer, Rupert Sandbrink, Ludwig Kappos, Bernard MJ Uitdehaag

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 398 KB

english, 2009

20

INTERLEUKIN 15 STIMULATES PRODUCTION OF MATRIX METALLOPROTEINASE-9 AND TISSUE INHIBITOR OF METALLOPROTEINASE-1 BY HUMAN PERIPHERAL BLOOD MONONUCLEAR CELLS

Cris S. Constantinescu, Caroline Grygar, Ludwig Kappos, David Leppert

Journal:

Année:

2001

Langue:

english

Fichier:

PDF, 165 KB

english, 2001

21

Effect of early versus delayed interferon beta-1b treatment on disability after a first clinical event suggestive of multiple sclerosis: a 3-year follow-up analysis of the BENEFIT study

Ludwig Kappos, Mark S Freedman, Chris H Polman, Gilles Edan, Hans-Peter Hartung, David H Miller, Xavier Montalbán, Frederik Barkhof, Ernst-Wilhelm Radü, Lars Bauer, Susanne Dahms, Vivian Lanius, Chris

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 183 KB

english, 2007

22

Efficacy and safety of oral fumarate in patients with relapsing-remitting multiple sclerosis: a multicentre, randomised, double-blind, placebo-controlled phase IIb study

Ludwig Kappos, Ralf Gold, David H Miller, David G MacManus, Eva Havrdova, Volker Limmroth, Chris H Polman, Klaus Schmierer, Tarek A Yousry, Minhua Yang, Mefkûre Eraksoy, Eva Meluzinova, Ivan Rektor, K

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 209 KB

english, 2008

23

Ocrelizumab in relapsing-remitting multiple sclerosis: a phase 2, randomised, placebo-controlled, multicentre trial

Ludwig Kappos, David Li, Peter A Calabresi, Paul O'Connor, Amit Bar-Or, Frederik Barkhof, Ming Yin, David Leppert, Robert Glanzman, Jeroen Tinbergen, Stephen L Hauser

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 337 KB

english, 2011

24

Ocrelizumab in multiple sclerosis: risks and benefits – Author's reply

Ludwig Kappos, David Leppert, Jeroen Timmermann, Robert Glanzman, Stephen Hauser

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 80 KB

english, 2012

25

Predictive value of gadolinium-enhanced magnetic resonance imaging for relapse rate and changes in disability or impairment in multiple sclerosis: a meta-analysis

Ludwig Kappos, David Moeri, Ernst Wilhelm Radue, Andreas Schoetzau, Kati Schweikert, Frederik Barkhof, David Miller, Charles RG Guttmann, Howard L Weiner, Claudio Gasperini, Massimo Filippi

Journal:

Année:

1999

Langue:

english

Fichier:

PDF, 116 KB

english, 1999

26

Matrix metalloproteinases: multifunctional effectors of inflammation in multiple sclerosis and bacterial meningitis

David Leppert, Raija L.P. Lindberg, Ludwig Kappos, Stephen L. Leib

Journal:

Brain Research Reviews

Année:

2001

Langue:

english

Fichier:

PDF, 342 KB

english, 2001

27

Monoclonal Antibodies and Recombinant Immunoglobulins for the Treatment of Multiple Sclerosis

Gensicke, Henrik, Leppert, David, Yaldizli, ÃzgÃ¼r, Lindberg, Raija L.P., Mehling, Matthias, Kappos, Ludwig, Kuhle, Jens

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 293 KB

english, 2012

28

A Randomized, Placebo-Controlled Trial of Natalizumab for Relapsing Multiple Sclerosis

Polman, Chris H., O'Connor, Paul W., Havrdova, Eva, Hutchinson, Michael, Kappos, Ludwig, Miller, David H., Phillips, J. Theodore, Lublin, Fred D., Giovannoni, Gavin, Wajgt, Andrzej, Toal, Martin, Lynn

Journal:

Boston Medical and Surgical Journal

Année:

2006

Langue:

english

Fichier:

PDF, 211 KB

english, 2006

29

Who Will Bankroll the Next Big Idea?

Kappos, David J.

Journal:

Scientific American

Année:

2013

Langue:

english

Fichier:

PDF, 1.87 MB

english, 2013

30

Molecular mechanism underlying the impact of vitamin D on disease activity of MS

Munger, Kassandra L., Köchert, Karl, Simon, Kelly C., Kappos, Ludwig, Polman, Chris H., Freedman, Mark S., Hartung, Hans P., Miller, David H., Montalbán, Xavier, Edan, Gilles, Barkhof, Frederik, Pleim

Journal:

Annals of Clinical and Translational Neurology

Année:

2014

Langue:

english

Fichier:

PDF, 655 KB

english, 2014

31

Tweaks to the Idea Factory

Kappos, David J.

Journal:

Scientific American

Année:

2013

Langue:

english

Fichier:

PDF, 616 KB

english, 2013

32

MRI monitoring of immunomodulation in relapse-onset multiple sclerosis trials

Barkhof, Frederik, Simon, Jack H., Fazekas, Franz, Rovaris, Marco, Kappos, Ludwig, de Stefano, Nicola, Polman, Chris H., Petkau, John, Radue, Ernst W., Sormani, Maria P., Li, David K., O'Connor, Paul,

Journal:

Nature Reviews Neurology (formerly Nature Clinical Practice Neurology)

Année:

2011

Langue:

english

Fichier:

PDF, 221 KB

english, 2011

33

Discrepancies in the interpretation of clinical symptoms and signs in the diagnosis of multiple sclerosis. A proposal for standardization

Uitdehaag, Bernard MJ, Kappos, Ludwig, Bauer, Lars, Freedman, Mark S, Miller, David, Sandbrink, Rupert, Polman, Chris H

Journal:

Multiple Sclerosis Journal

Année:

2005

Langue:

english

Fichier:

PDF, 167 KB

english, 2005

34

Myelin Autoreactivity in Multiple Sclerosis: Recognition of Myelin Basic Protein in the Context of HLA-DR2 Products by T Lymphocytes of Multiple- Sclerosis Patients and Healthy Donors

Martin Pette, Kyoko Fujita, David Wilkinson, Daniel M. Altmann, John Trowsdale, Gerhard Giegerich, Ari Hinkkanen, Jorg T. Epplen, Ludgwig Kappos and Hartmut Wekerle

Journal:

Proceedings of the National Academy of Sciences

Année:

1990

Langue:

english

Fichier:

PDF, 954 KB

english, 1990

35

Magnetic Resonance Imaging Predictors of Conversion to Multiple Sclerosis in the BENEFIT Study

Moraal, Bastiaan, Pohl, Christoph, Uitdehaag, Bernard M. J., Polman, Chris H., Edan, Gilles, Freedman, Mark S., Hartung, Hans-Peter, Kappos, Ludwig, Miller, David H., Montalban, Xavier, Lanius, Vivian

Journal:

Archives of Neurology

Année:

2009

Langue:

english

Fichier:

PDF, 160 KB

english, 2009

36

Safety and Efficacy of Siponimod (BAF312) in Patients With Relapsing-Remitting Multiple Sclerosis

Kappos, Ludwig, Li, David K. B., Stüve, Olaf, Hartung, Hans-Peter, Freedman, Mark S., Hemmer, Bernhard, Rieckmann, Peter, Montalban, Xavier, Ziemssen, Tjalf, Hunter, Brian, Arnould, Sophie, Wallström,

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 453 KB

english, 2016

37

Prognostic factors for long-term outcomes in relapsing–remitting multiple sclerosis

Traboulsee, Anthony L, Cornelisseª, Peter, Sandberg-Wollheim, Magnhild, Uitdehaag, Bernard MJ, Kappos, Ludwig, Jongen, Peter J, Constantinescu, Cris S, di Cantogno, Elisabetta Verdun, Li, David KB

Journal:

Multiple Sclerosis Journal - Experimental Translational and Clinical

Année:

2016

Langue:

english

Fichier:

PDF, 202 KB

english, 2016

38

Fluid biomarker and electrophysiological outcome measures for progressive MS trials

Barro, Christian, Leocani, Letizia, Leppert, David, Comi, Giancarlo, Kappos, Ludwig, Kuhle, Jens

Journal:

Multiple Sclerosis Journal

Année:

2017

Langue:

english

Fichier:

PDF, 472 KB

english, 2017

39

Preliminary results of the opera i and opera ii open-label extension study

Naismith, Robert, Cascione, Mark, Grimaldi, Luigi, Hauser, Stephen, Kappos, Ludwig, Montalban, Xavier, Wolinsky, Jerry, Chin, Peter, Garren, Hideki, Julian, Laura, Model, Fabian, Honeycutt, David

Journal:

Journal of Neurology Neurosurgery & Psychiatry

Année:

2017

Langue:

english

Fichier:

PDF, 49 KB

english, 2017

40

Interoperating Standards: Formal, Informal and Open Source Development Model Ecosystems in Transition

Atlass, Michael, Kappos, David, Bassey, Patrick

Journal:

IEEE Communications Standards Magazine

Année:

2017

Langue:

english

Fichier:

PDF, 105 KB

english, 2017

41

Comparative analyses and structural insights of the novel cytochrome P450 fusion protein family CYP5619 in Oomycetes

Bamal, Hans Denis, Chen, Wanping, Mashele, Samson Sitheni, Nelson, David R., Kappo, Abidemi Paul, Mosa, Rebamang Anthony, Yu, Jae-Hyuk, Tuszynski, Jack A., Syed, Khajamohiddin

Journal:

Scientific Reports

Année:

2018

Langue:

english

Fichier:

PDF, 2.29 MB

english, 2018

42

Brain atrophy and disability worsening in primary progressive multiple sclerosis: insights from the INFORMS study

Miller, David H., Lublin, Fred D., Sormani, Maria Pia, Kappos, Ludwig, Yaldizli, Özgür, Freedman, Mark S., Cree, Bruce A. C., Weiner, Howard L., Lubetzki, Catherine, Hartung, Hans-Peter, Montalban, Xa

Journal:

Annals of Clinical and Translational Neurology

Année:

2018

Langue:

english

Fichier:

PDF, 244 KB

english, 2018

43

[Lecture Notes in Mathematics] Symposium on Probability Methods in Analysis Volume 31 || Invariant and non-invariant measures

Grenander, Ulf, Guber, Siegfried, Jacobs, Konrad, Kappos, Demetrios A., Kellerer, Hans G., Kendall, David. G., Kounias, Eustratios, Kristensen, Povl, Mejlbo, Lars, Poulsen, Ebbe Thue, Loynes, R. M., L

Année:

1967

Langue:

english

Fichier:

PDF, 964 KB

english, 1967

44

[Lecture Notes in Mathematics] Symposium on Probability Methods in Analysis Volume 31 || Recent developments in axiomatic potential theory

Grenander, Ulf, Guber, Siegfried, Jacobs, Konrad, Kappos, Demetrios A., Kellerer, Hans G., Kendall, David. G., Kounias, Eustratios, Kristensen, Povl, Mejlbo, Lars, Poulsen, Ebbe Thue, Loynes, R. M., L

Année:

1967

Langue:

english

Fichier:

PDF, 440 KB

english, 1967

45

[Lecture Notes in Mathematics] Symposium on Probability Methods in Analysis Volume 31 || Extension of stationary processes

Grenander, Ulf, Guber, Siegfried, Jacobs, Konrad, Kappos, Demetrios A., Kellerer, Hans G., Kendall, David. G., Kounias, Eustratios, Kristensen, Povl, Mejlbo, Lars, Poulsen, Ebbe Thue, Loynes, R. M., L

Année:

1967

Langue:

english

Fichier:

PDF, 64 KB

english, 1967

46

Comparative Analyses of Cytochrome P450s and Those Associated with Secondary Metabolism in Bacillus Species

Mthethwa, Bongumusa, Chen, Wanping, Ngwenya, Mathula, Kappo, Abidemi, Syed, Puleng, Karpoormath, Rajshekhar, Yu, Jae-Hyuk, Nelson, David, Syed, Khajamohiddin

Journal:

International Journal of Molecular Sciences

Année:

2018

Langue:

english

Fichier:

PDF, 3.92 MB

english, 2018

47

[Lecture Notes in Mathematics] Symposium on Probability Methods in Analysis Volume 31 || Some problems arising from spectral analysis

Grenander, Ulf, Guber, Siegfried, Jacobs, Konrad, Kappos, Demetrios A., Kellerer, Hans G., Kendall, David. G., Kounias, Eustratios, Kristensen, Povl, Mejlbo, Lars, Poulsen, Ebbe Thue, Loynes, R. M., L

Année:

1967

Langue:

english

Fichier:

PDF, 679 KB

english, 1967

48

[Lecture Notes in Mathematics] Symposium on Probability Methods in Analysis Volume 31 || On the potential theory of linear, homogeneous parabolic partial differential equations of second order

Grenander, Ulf, Guber, Siegfried, Jacobs, Konrad, Kappos, Demetrios A., Kellerer, Hans G., Kendall, David. G., Kounias, Eustratios, Kristensen, Povl, Mejlbo, Lars, Poulsen, Ebbe Thue, Loynes, R. M., L

Année:

1967

Langue:

english

Fichier:

PDF, 341 KB

english, 1967

49

Cytochrome P450 Monooxygenase CYP139 Family Involved in the Synthesis of Secondary Metabolites in 824 Mycobacterial Species

Syed, Puleng Rosinah, Chen, Wanping, Nelson, David R., Kappo, Abidemi Paul, Yu, Jae-Hyuk, Karpoormath, Rajshekhar, Syed, Khajamohiddin

Journal:

International Journal of Molecular Sciences

Année:

2019

Langue:

english

Fichier:

PDF, 1.73 MB

english, 2019

50

Blood neurofilament light as a potential endpoint in Phase 2 studies in MS

Sormani, Maria Pia, Haering, Dieter A., Kropshofer, Harald, Leppert, David, Kundu, Uma, Barro, Christian, Kappos, Ludwig, Tomic, Davorka, Kuhle, Jens

Journal:

Annals of Clinical and Translational Neurology

Année:

2019

Langue:

english

Fichier:

PDF, 214 KB

english, 2019